Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553599 | 0.81 | MAPT (0.64) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6554561 | 0.81 | MAPT (0.64) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6554557 | 0.80 | MAPT (0.62) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6553303 | 0.78 | MAPT (0.54) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6553223 | 0.76 | MAPT (0.59) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL26906943 | 0.74 | MAPT (0.70) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL29507647 | 0.72 | MAPT (0.69) | MAPTL3MBTL1SMN1; SMN2POLBCCR2 | |
| SCHEMBL1138740 | 0.72 | MAPT (0.69) | MAPTL3MBTL1SMN1; SMN2POLBCCR2 | |
| SCHEMBL357928 | 0.72 | PDK1 (0.55) | MAPTTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL27182938 | 0.71 | L3MBTL1 (0.55) | MAPTTDP1L3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283216-A1 | FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283216-A1 | FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES | CBR3, CBR1, Q6ZSR9 | MAPT 4750/4885TDP1 2075/4885L3MBTL1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.