SCHEMBL135837

SCHEMBL135837

Fc1cccc(I)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL25169958 0.97 ACHE (0.46)
SCHEMBL28964841 0.92 ACHE (0.42)
Cyanide SCHEMBL27758975 0.92 ACHE (0.42)
SCHEMBL6561473 0.92 ACHE (0.46)
SCHEMBL27882252 0.88 PARP1 (0.42)
SCHEMBL28484445 0.86 PARP1 (0.41)
SCHEMBL27739769 0.86 NFE2L2 (0.41)
SCHEMBL18251126 0.85 TAAR1 (0.54)
SCHEMBL17608841 0.79 MAP4K4 (0.41)
SCHEMBL170090 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574107-A Method for synthesizing aryl thiobenzothiazole compound based on cuprous chloride 苏州大学 2026-02-27 CN claimed
US-20250309354-A1 ELECTROLYTE COMPRISING AROMATIC COMPOUND WITH NON-FLUORINE HALOGEN SUBSTITUTE AND BATTERIES COMPRISING SAME FACTORIAL INC. 2025-10-02 US claimed
CN-119346167-A Catalytic system and method for synthesizing diaryl acetylene from calcium carbide and iodo aromatic hydrocarbon 石河子大学 2025-01-24 CN claimed
CN-116178092-B Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2024-11-22 CN claimed
CN-117430632-A Ortho-bis-quaternary phosphonium salt derivative and preparation method thereof 华东理工大学 2024-01-23 CN claimed
CN-116178092-A Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2023-05-30 CN claimed
CN-110683926-B Preparation method of carboxylic acid aryl ester compound 北京大学深圳研究生院 2022-11-04 CN claimed
CN-114394891-A Compound prepared by catalyzing chalcone with monovalent iodine reagent, and preparation method and application thereof 化学与精细化工广东省实验室 2022-04-26 CN claimed
CN-112645938-A Oxetane derivative with anti-tumor activity and preparation method and application thereof 山东省青州荣军医院 2021-04-13 CN claimed
CN-108383779-B Preparation method of 3 '-aryl-2, 2' -bipyridine-6-formamide derivative 华侨大学 2021-02-02 CN claimed
US-8399680-B2 Arylamine synthesis method CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-03-19 US claimed
US-20100298571-A1 ARYLAMINE SYNTHESIS METHOD CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 US claimed
EP-1362860-B1 Method for producing tetrakis (fluoraryl)borate magnesium compound NIPPON CATALYTIC CHEM IND (JP) 2010-09-15 EP claimed
EP-2197829-A2 ARYLAMINE SYNTHESIS METHOD Centre National de la Recherche Scientifique (C.N.R.S.) (FR) 2010-06-23 EP claimed
WO-2009050366-A2 ARYLAMINE SYNTHESIS METHOD CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2009-04-23 WO claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
US-7205441-B2 Method for producing tetrakis (fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-17 US claimed
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-20 US claimed
EP-1362860-A1 Method for producing tetrakis (fluoroaryl) borate magnesium compound Nippon Shokubai Co., Ltd. (JP) 2003-11-19 EP claimed