Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2A | Q12879 | 2/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506485 | 0.91 | GRIN2A (0.70) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL19506280 | 0.91 | GRIN2A (0.70) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL21257625 | 0.89 | GRIN2A (0.58) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL21257629 | 0.89 | GRIN2A (0.58) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL21257623 | 0.89 | GRIN2A (0.58) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL21257887 | 0.88 | GRIN2A (0.57) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL16860684 | 0.88 | CYP2D6 (0.67) | GRIN2AGRIN1GRIN2BLMNAMEN1 | |
| SCHEMBL933404 | 0.88 | CYP2D6 (0.67) | GRIN2AGRIN1GRIN2BLMNAMEN1 | |
| SCHEMBL21257788 | 0.87 | GRIN2A (0.59) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 | |
| SCHEMBL21257866 | 0.87 | GRIN2A (0.59) | GRIN2AGRIN1GRIN2BGPBAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110314166-A | Application of the Tauro ursodesoxy cholic acid in anti-hand-foot-and-mouth-disease poison and vesicular stomatitis virus drug | 武汉大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-105891351-B | A kind of new Tauro ursodesoxy cholic acid content and the detection method in relation to substance | 中山百灵生物技术有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-104382911-B | Application of the Tauro ursodesoxy cholic acid salt as active component in treatment Echinococcus Granulosus Cysts medicine is prepared | 姜玉峰 | 2017-09-15 | — | — | CN | disclosed |
| CN-106031731-A | New uses of tauroursodeoxycholic acid | 中国医学科学院基础医学研究所 | 2016-10-19 | — | — | CN | disclosed |
| CN-105699501-A | Method for detecting impurities in tauroursodeoxycholic acid through high performance liquid chromatograph | 成都欣捷高新技术开发有限公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103445007-B | Tauro ursodesoxy cholic acid is alleviating the application in chicken heat shock as feed addictive | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2015-09-30 | — | — | CN | disclosed |
| US-9085602-B1 | Facial amphiphiles and methods of use | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-07-21 | — | — | US | disclosed |
| CN-104382911-A | Application of tauroursodeoxycholic acid salt used as active ingredient in preparation of drug for treating echinococcosis | JIANG YUFENG | 2015-03-04 | — | — | CN | disclosed |
| CN-103919787-A | Pharmaceutical application of tauroursodeoxycholic acid and acceptable salts thereof | UNIV XIAMEN | 2014-07-16 | — | — | CN | disclosed |
| CN-103445007-A | Application of tauroursodeoxycholic acid as feed additive in aspect of alleviating chicken heat stress | UNIV SOUTH CHINA AGRICULT | 2013-12-18 | — | — | CN | disclosed |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2009-07-09 | — | — | US | disclosed |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2008-10-09 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2007-10-04 | — | — | US | disclosed |
| US-7226577-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING, S. P. A. (IT) | 2007-06-05 | — | — | US | disclosed |
| US-20060239914-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | disclosed |
| US-20060241018-A1 | Linkers for radiopharmaceutical compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | disclosed |
| CN-1738652-A | Improved linkers for pharmaceutical compounds | BRACCO IMAGING SPA (IT) | 2006-02-22 | — | — | CN | disclosed |
| US-20060018830-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-01-26 | — | — | US | disclosed |
| US-4117121-A | 3ALPHA, 12ALPHA DIHYDROXYCHOLANE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239914-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | GRIN2A 1511/4885GRIN1 1289/4885GRIN2B 1943/4885 |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | GRIN2A 1665/4885GRIN1 1513/4885GRIN2B 2202/4885 |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | GRIN2A 1665/4885GRIN1 1513/4885GRIN2B 2202/4885 |
| US-20060018830-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | GRIN2A 1511/4885GRIN1 1289/4885GRIN2B 1943/4885 |
| US-20060241018-A1 | Linkers for radiopharmaceutical compounds | VIP, QPCT, NPPA | GRIN2A 4756/4885GRIN1 4739/4885GRIN2B 4659/4885 |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | GRPR, MRGPRX2, MRGPRX1 | GRIN2A 2131/4885GRIN1 1823/4885GRIN2B 1596/4885 |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | GRPR, MRGPRX1, BRS3 | GRIN2A 2616/4885GRIN1 1807/4885GRIN2B 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.