Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFPT1 | Q06210 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584359 | 1.00 | GFPT1 (0.49) | GFPT1CASRGAAMEN1KMT2A | |
| SCHEMBL1768690 | 0.86 | DDAH1 (0.44) | GFPT1GAAMEN1KMT2AHPGD | |
| SCHEMBL1768693 | 0.86 | DDAH1 (0.44) | GFPT1GAAMEN1KMT2AHPGD | |
| SCHEMBL2237950 | 0.80 | GFPT1 (0.45) | GFPT1HPGDSLC7A5DDAH1 | |
| SCHEMBL2237956 | 0.80 | GFPT1 (0.45) | GFPT1HPGDSLC7A5DDAH1 | |
| SCHEMBL6468831 | 0.79 | GAA (0.55) | GAAMEN1KMT2AHPGD | |
| SCHEMBL1768739 | 0.79 | CASR (0.45) | GFPT1CASRSLC7A5 | |
| SCHEMBL1768743 | 0.79 | CASR (0.45) | GFPT1CASRSLC7A5 | |
| SCHEMBL13585557 | 0.78 | CASR (0.43) | GFPT1CASRSLC7A5 | |
| SCHEMBL13585036 | 0.78 | GFPT1 (0.42) | GFPT1CASRMEN1KMT2ASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754038-B2 | Template-fixed peptidomimetics with CCR10 antagonistic activity | POLYPHOR AG (CH) | 2014-06-17 | — | — | US | disclosed |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | CCR10, CCR1, CCRL2 | GFPT1 3069/4885CASR 469/4885GAA 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.