Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767114 | 0.93 | MAPT (0.47) | MAPTTHRBKMT2ATP53BACE1 | |
| SCHEMBL14767151 | 0.93 | KMT2A (0.45) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL12741887 | 0.91 | ALDH1A1 (0.41) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL12741858 | 0.91 | MAPT (0.43) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL12741893 | 0.90 | MAPT (0.42) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL12822521 | 0.90 | KMT2A (0.50) | MAPTKMT2ABACE1CYP2C19APP | |
| SCHEMBL14766751 | 0.89 | FFAR1 (0.46) | MAPTTHRBKMT2AFFAR1CYP2C19 | |
| SCHEMBL14766141 | 0.89 | MAPT (0.50) | MAPTTHRBKMT2ATP53BACE1 | |
| SCHEMBL12741863 | 0.88 | MAPT (0.50) | MAPTTHRBKMT2ATP53FFAR1 | |
| SCHEMBL12741868 | 0.87 | KCNQ3 (0.37) | MAPTTHRBKMT2AFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |