Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12823666 | 0.93 | PTGS2 (0.36) | PTGS2FFAR4FFAR1CAMKK1CAMKK2 | |
| SCHEMBL14765855 | 0.92 | FFAR4 (0.37) | FFAR4FFAR1CAMKK1CAMKK2 | |
| SCHEMBL12716197 | 0.92 | MEN1 (0.33) | PTGS2FFAR4FFAR1CAMKK1CAMKK2 | |
| SCHEMBL12821130 | 0.91 | MEN1 (0.33) | MEN1KMT2AAPP | |
| SCHEMBL12734337 | 0.89 | FFAR4 (0.34) | FFAR4FFAR1CAMKK1CAMKK2 | |
| SCHEMBL12822617 | 0.89 | ACACB (0.32) | ACACB | |
| SCHEMBL12734340 | 0.89 | FFAR4 (0.33) | FFAR4FFAR1CAMKK1CAMKK2 | |
| SCHEMBL13586337 | 0.89 | LMNA (0.35) | FFAR4FFAR1CAMKK1CAMKK2HTT | |
| SCHEMBL12716432 | 0.89 | FFAR4 (0.32) | FFAR4FFAR1CAMKK1CAMKK2 | |
| SCHEMBL12734331 | 0.88 | FFAR4 (0.33) | FFAR4FFAR1CAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |