Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CPS1 | P31327 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766390 | 0.93 | HTR1A (0.34) | HCRTR2GPR119KCNH2HTR1ANAAA | |
| SCHEMBL12718656 | 0.93 | NAAA (0.38) | HCRTR2KCNH2HTR1ACACNA2D1CACNA2D2 | |
| SCHEMBL12736673 | 0.91 | GPR119 (0.33) | HCRTR2GPR119KCNH2HTR1ANAAA | |
| SCHEMBL12822816 | 0.91 | NAAA (0.39) | HCRTR2GPR119HTR1ANAAAMAOA | |
| SCHEMBL12736666 | 0.90 | GPR119 (0.35) | HCRTR2GPR119KCNH2HTR1ANAAA | |
| SCHEMBL10302631 | 0.90 | GPR119 (0.37) | HCRTR2GPR119KCNH2HTR1ANAAA | |
| SCHEMBL14765918 | 0.89 | CRBN (0.33) | HCRTR2GPR119KCNH2HTR1ANAAA | |
| SCHEMBL10303223 | 0.89 | NAAA (0.37) | HCRTR2GPR119HTR1ANAAACPS1 | |
| SCHEMBL12736672 | 0.89 | GPR119 (0.35) | HCRTR2GPR119KCNH2HTR1ANAAA | |
| SCHEMBL12736667 | 0.89 | OPRL1 (0.34) | HCRTR2GPR119HTR1ANAAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |