Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 5/20 | 0.41 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13587324 | 0.99 | XDH (0.43) | XDHNOS1DHFRPNPMEN1 | |
| SCHEMBL13587313 | 0.90 | XDH (0.52) | XDHNOS1DHFRPNPMEN1 | |
| SCHEMBL13587330 | 0.82 | IP6K1 (0.39) | NOS1PNP | |
| SCHEMBL13587320 | 0.81 | IP6K1 (0.37) | NOS1PNP | |
| SCHEMBL13587331 | 0.79 | NOS1 (0.32) | NOS1MEN1KMT2A | |
| SCHEMBL13587328 | 0.75 | ADORA2A (0.58) | — | |
| SCHEMBL13587335 | 0.75 | PNP (0.40) | NOS1PNPMEN1KMT2A | |
| SCHEMBL13587341 | 0.75 | PNP (0.62) | PNPMEN1KMT2A | |
| SCHEMBL13587315 | 0.73 | ADORA2A (0.59) | — | |
| SCHEMBL13587326 | 0.69 | PNP (0.38) | XDHDHFRPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090299049-A1 | Bicyclic Compounds and Their Use | REPLIZYME LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299049-A1 | Bicyclic Compounds and Their Use | ERCC4, PARP1, ERCC5 | XDH 1858/4885NOS1 1405/4885DHFR 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.