Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13587320 | 0.99 | IP6K1 (0.37) | IP6K1IP6K3IP6K2ADORA3ADORA2A | |
| SCHEMBL13587316 | 0.90 | IP6K1 (0.45) | IP6K1IP6K3IP6K2ADORA3ADORA2A | |
| SCHEMBL13587332 | 0.82 | XDH (0.43) | NOS1PNP | |
| SCHEMBL13587324 | 0.81 | XDH (0.43) | NOS1PNP | |
| SCHEMBL13587328 | 0.78 | ADORA2A (0.58) | ADORA3ADORA2AADORA1 | |
| SCHEMBL13587315 | 0.77 | ADORA2A (0.59) | ADORA3ADORA2AADORA1 | |
| SCHEMBL13587331 | 0.75 | NOS1 (0.32) | ADORA2AALDH1A1NOS1KDM4EHSD17B10 | |
| SCHEMBL13587318 | 0.73 | NOS1 (0.32) | ADORA2AALDH1A1NOS1KDM4EHSD17B10 | |
| SCHEMBL13587313 | 0.72 | XDH (0.52) | ADORA3ADORA2AADORA1NOS1KDM4E | |
| SCHEMBL13587327 | 0.70 | ALDH1A1 (0.34) | ADORA3HPRT1ALDH1A1MAPK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090299049-A1 | Bicyclic Compounds and Their Use | REPLIZYME LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299049-A1 | Bicyclic Compounds and Their Use | ERCC4, PARP1, ERCC5 | IP6K1 2543/4885IP6K3 2707/4885IP6K2 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.