Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13587757 | 0.89 | NR3C2 (0.58) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL13587753 | 0.89 | NR3C2 (0.46) | NR3C2TSHRADORA3CACNA1CCYP2C9 | |
| SCHEMBL8258466 | 0.88 | NR3C2 (0.52) | NR3C2TSHRALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL8255204 | 0.88 | ABCB11 (0.45) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL13587803 | 0.88 | NR3C2 (0.58) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL13587807 | 0.86 | NR3C2 (0.63) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL13587742 | 0.86 | NR3C2 (0.58) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL8261064 | 0.85 | NR3C2 (0.58) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL13587738 | 0.84 | NR3C2 (0.55) | NR3C2TSHRTBXA2RADRA1ASLC6A3 | |
| SCHEMBL13587770 | 0.84 | NR3C2 (0.57) | NR3C2TSHRTBXA2RADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298872-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM LLC (BM) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298872-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | TRPV1, TRPV2, TRPV6 | NR3C2 12/4885TSHR 754/4885TBXA2R 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.