Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13632750 | 0.86 | TACR1 (0.43) | TACR1LCKEGFRBACE1ALDH1A1 | |
| SCHEMBL6534778 | 0.85 | TACR1 (0.48) | TACR1LCKEGFRTP53CA2 | |
| SCHEMBL6534780 | 0.85 | TACR1 (0.48) | TACR1LCKEGFRTP53CA2 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468858 | 0.83 | TACR1 (0.58) | TACR1BACE1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL14370511 | 0.83 | TACR1 (0.58) | TACR1BACE1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468756 | 0.83 | TACR1 (0.58) | TACR1BACE1 | |
| SCHEMBL13588694 | 0.83 | TACR1 (0.48) | TACR1LCKEGFRALDH1A1MAPT | |
| SCHEMBL6224832 | 0.82 | TACR1 (0.53) | TACR1LCKBACE1TP53ALDH1A1 | |
| SCHEMBL3282594 | 0.82 | TACR1 (0.53) | TACR1LCKBACE1TP53ALDH1A1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL25257912 | 0.82 | TACR1 (0.56) | TACR1EGFRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318171-B2 | Neurotoxic oligomers | PRANA BIOTECHNOLOGY LIMITED (AU) | 2012-11-27 | — | — | US | disclosed |
| US-20090297538-A1 | NEUROTOXIC OLIGOMERS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2009-12-03 | — | — | US | disclosed |