Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13589338 | 0.99 | KDM4E (0.54) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL13589339 | 0.85 | CA12 (0.64) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL24832744 | 0.80 | SLC18A1 (0.67) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL24710370 | 0.76 | SMN1; SMN2 (0.56) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL13370590 | 0.75 | KDM4E (0.77) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL18994935 | 0.75 | KDM4E (0.80) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL24710368 | 0.74 | ENPP2 (0.57) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL14527910 | 0.74 | SLC18A1 (0.65) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL12987557 | 0.74 | KDM4E (0.78) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL29435303 | 0.74 | KDM4E (0.78) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629437-B2 | Fluorogenic materials and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-12-08 | — | — | US | disclosed |