Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | F13A1 | P00488 | 2/20 | 0.38 |
| ▸ | TGM1 | P22735 | 2/20 | 0.38 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13591016 | 0.88 | HTR6 (0.39) | HTR6ATMAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL4398890 | 0.88 | HTR6 (0.39) | HTR6ATMAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL4398888 | 0.88 | HTR6 (0.39) | HTR6ATMAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL4394396 | 0.76 | HTR6 (0.47) | HTR6ATMLMNAKMT2AMEN1 | |
| SCHEMBL13592436 | 0.72 | MAPK1 (0.36) | KMT2AMEN1 | |
| SCHEMBL14287207 | 0.68 | ALDH1A1 (0.40) | ATMKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL6612849 | 0.68 | HTR6 (0.46) | HTR6KMT2AMEN1ALDH1A1 | |
| SCHEMBL14287186 | 0.67 | L3MBTL1 (0.41) | ATMKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4370479 | 0.67 | HTR6 (0.47) | HTR6LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL30259939 | 0.67 | HTR6 (0.47) | HTR6LMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632948-B2 | Method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives | NEUROSEARCH A/S (DK) | 2009-12-15 | — | — | US | disclosed |