Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487844 | 0.90 | MAPT (0.62) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL487843 | 0.90 | MAPT (0.62) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8316277 | 0.78 | MAPT (0.56) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10910531 | 0.75 | MEN1 (0.46) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL734790 | 0.69 | KMT2A (1.00) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL734791 | 0.69 | KMT2A (1.00) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6714200 | 0.69 | MAPT (0.62) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3065879 | 0.69 | MAPT (0.62) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3065881 | 0.69 | MAPT (0.62) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6714202 | 0.69 | MAPT (0.62) | GAAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067458-B2 | Alkoxyalkyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | US | disclosed |
| US-7495018-B2 | Substituted 1,3-thiazole compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20040053973-A1 | Substituted 1,3-thiazole compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1268474-A2 | SUBSTITUTED 1,3-THIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074811-A2 | SUBSTITUTED 1,3-THIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053973-A1 | Substituted 1,3-thiazole compounds, their production and use | MAPK1, MAP4K2, MAPK4 | GAA 4026/4885MAPT 1064/4885MEN1 3676/4885 |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | DDT, EBP, TET1 | GAA 883/4885MAPT 4800/4885MEN1 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.