Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487843 | 0.86 | MAPT (0.62) | MAPTSENP7GAAALDH1A1GFER | |
| SCHEMBL487844 | 0.86 | MAPT (0.62) | MAPTSENP7GAAALDH1A1GFER | |
| Pyrrole SCHEMBL1359313 | 0.78 | GAA (0.53) | MAPTSENP7GAAALDH1A1GFER | |
| SCHEMBL24629103 | 0.76 | SENP7 (0.64) | MAPTSENP7GAAALDH1A1GFER | |
| SCHEMBL11545496 | 0.75 | MAPT (0.86) | MAPTSENP7GAAALDH1A1GFER | |
| SCHEMBL11545493 | 0.75 | MAPT (0.86) | MAPTSENP7GAAALDH1A1GFER | |
| SCHEMBL20878193 | 0.73 | RAB9A (0.47) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28908620 | 0.72 | MAPT (0.62) | MAPTSENP7GAAALDH1A1GFER | |
| SCHEMBL11673798 | 0.72 | MAPT (1.00) | MAPTGAAALDH1A1GFERSMN1; SMN2 | |
| SCHEMBL11673800 | 0.72 | MAPT (1.00) | MAPTGAAALDH1A1GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | disclosed |