Sugi Predict

Sugi Predict / Compounds / SCHEMBL734790

SCHEMBL734790

SCHEMBL734790

Oc1ccccc1/C=N/Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 1.00
▸ MAPT P10636 7/20 1.00
▸ MEN1 O00255 6/20 1.00
▸ ALDH1A1 P00352 5/20 1.00
▸ HPGD P15428 5/20 1.00
▸ GAA P10253 5/20 1.00
▸ GFER P55789 1/20 1.00
▸ SMN1; SMN2 Q16637 4/20 0.69
▸ NPC1 O15118 1/20 0.69
▸ RAB9A P51151 1/20 0.69
▸ CASP3 P42574 1/20 0.65
▸ SENP8 Q96LD8 1/20 0.65
▸ SENP7 Q9BQF6 1/20 0.65
▸ SENP6 Q9GZR1 1/20 0.65
▸ CTRC Q99895 1/20 0.58
▸ DUSP3 P51452 1/20 0.58
▸ PTPN5 P54829 1/20 0.58
▸ PTPN11 Q06124 1/20 0.58
▸ NOX1 Q9Y5S8 1/20 0.57
▸ KDM4E B2RXH2 8/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL734791 1.00 KMT2A (1.00) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL31638206 1.00 KMT2A (1.00) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL1132176 0.82 MEN1 (0.71) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL30602635 0.82 MEN1 (0.71) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL1132125 0.82 MEN1 (0.71) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL8265904 0.80 MEN1 (0.66) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL8264549 0.79 KMT2A (0.64) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL20806242 0.78 MAPT (0.64) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL7063429 0.78 CTRC (0.69) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL3065879 0.77 MAPT (0.62) KMT2AMAPTMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287149-A1 Enhancers of protein degradation MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) 2011-02-23 — — EP claimed
US-RE50527-E1 Covalent inhibitors of KRAS G12C ARAXES PHARMA LLC (US) 2025-08-12 — — US disclosed
EP-3268129-B1 OLEFIN OLIGOMERISATION PROCESS WITH A CATALYST COMPRISING A CHROMIUM COMPLEX WITH A PHOSPHACYCLE-CONTAINING LIGAND DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-18 — — EP disclosed
US-11896965-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-13 — — US disclosed
US-20240002325-A1 OXYLIPINS, PROCESSES FOR MAKING THE SAME, AND METHODS FOR USING THE SAME THE TRUSTEES OF INDIANA UNIVERSITY 2024-01-04 — — US disclosed
EP-3401314-B1 COVALENT INHIBITORS OF KRAS G12C ARAXES PHARMA LLC (US) 2023-11-08 — — EP disclosed
EP-3401314-B1 COVALENT INHIBITORS OF KRAS G12C ARAXES PHARMA LLC (US) 2023-11-08 — — EP disclosed
US-20230112954-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-13 — — US disclosed
US-11623209-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2023-04-11 — — US disclosed
US-11565995-B2 Methods of forming imines, imine-related and imine-derived compounds using green solvents THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-01-31 — — US disclosed
US-20040016363-A1 CORROSION-INHIBITING COATING VENTURE LENDING & LEASING, IV, INC. 2004-01-29 — — US disclosed
WO-2004009869-A2 CORROSION-INHIBITING COATING FOR METAL SURFACES UNIVERSITY OF DAYTON (US) 2004-01-29 — — WO disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 — — US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 — — US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 — — US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
US-4918045-A SUPPORTS, MICROCAPSULES CONTAINING COLORLESS ELECTRON-DONATING COLOR FORMER AND SOLVENT, AND ELECTRON-ACCEPTING DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 — — US disclosed
US-4876233-A NICKEL COMPOUNDS; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230112954-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM KMT2A 2522/4885MAPT 4266/4885MEN1 2246/4885
US-20240002325-A1 OXYLIPINS, PROCESSES FOR MAKING THE SAME, AND METHODS FOR USING THE SAME LIPA, FADS1, FADS2 KMT2A 4062/4885MAPT 4740/4885MEN1 2519/4885
US-11623209-B2 Process for oligomerization OXER1, NOD1, LIG1 KMT2A 4029/4885MAPT 2631/4885MEN1 1539/4885
US-11896965-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM KMT2A 2522/4885MAPT 4266/4885MEN1 2246/4885
US-11565995-B2 Methods of forming imines, imine-related and imine-derived compounds using green solvents IK, LDHB, IDH3B KMT2A 2431/4885MAPT 801/4885MEN1 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.