Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22647484 | 0.86 | CYP1A2 (0.46) | HRH4FLT3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL13593173 | 0.84 | HRH4 (0.55) | HRH4FLT3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4404148 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL29974441 | 0.81 | KDM4E (0.54) | FLT3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL10085352 | 0.81 | KDM4E (0.54) | FLT3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL30147671 | 0.76 | ALOX15 (0.50) | HRH4FLT3IDO1RAB9A | |
| SCHEMBL13593176 | 0.73 | DAO (0.55) | HRH4FLT3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30595727 | 0.73 | ALOX15 (0.53) | HRH4KDM4ERAB9A | |
| SCHEMBL11965473 | 0.72 | CYP1A2 (0.45) | HRH4FLT3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL22620744 | 0.71 | CYP1A2 (0.44) | HRH4FLT3KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390029-B1 | PHENYLINDOLES FOR THE TREATMENT OF HIV | IDENIX CAYMAN LTD (KY) | 2009-12-16 | — | — | EP | disclosed |