SCHEMBL135942

SCHEMBL135942

O=C1C=NC(c2ccccc2)O1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.39
SLC6A3 Q01959 1/20 0.39
LMNA P02545 3/20 0.38
POLB P06746 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CA2 P00918 1/20 0.37
MAPT P10636 3/20 0.34
MAPK1 P28482 2/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR2B P41595 1/20 0.34
KDM4E B2RXH2 3/20 0.34
ADORA3 P0DMS8 1/20 0.34
AR P10275 1/20 0.34
CYP19A1 P11511 1/20 0.34
MAOB P27338 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017262 0.78 TSHR (0.38) LMNAKMT2AMEN1ALDH1A1TSHR
SCHEMBL5855965 0.78 KDM4E (0.37) SLC6A3CYP3A4HTR2BKDM4E
SCHEMBL9360047 0.76 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL8884858 0.69 SPHK1 (0.43) SLC6A3LMNAALDH1A1TP53CYP3A4
SCHEMBL10833990 0.68 RAB9A (0.40) RAB9ASLC6A3LMNAPOLBKMT2A
SCHEMBL9843841 0.67 NFKB1 (0.36) LMNAPOLBKMT2AMEN1ALDH1A1
SCHEMBL13116176 0.64 TNKS (0.33) LMNAKMT2AALDH1A1CA2MAPT
SCHEMBL22733776 0.64 ALDH1A1 (0.46) RAB9ASLC6A3LMNAPOLBKMT2A
SCHEMBL22733775 0.64 ALDH1A1 (0.46) RAB9ASLC6A3LMNAPOLBKMT2A
SCHEMBL9255766 0.63 TSHR (0.38) KMT2AMEN1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120252-B Preparation method of ramipril key intermediate derivative 浙江工业大学 2024-10-29 CN claimed
CN-116120252-A Preparation method of ramipril key intermediate derivative 浙江工业大学 2023-05-16 CN claimed
WO-2002004020-A2 PATHOGEN RESISTANCE IN ORGANISMS MPB COLOGNE GMBH (DE) 2002-01-17 WO claimed
US-5911987-A NEWCASTLE DISEASE VIRUS DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 1999-06-15 US claimed
EP-0749487-A1 CELL SURFACE PROTEIN AND EFFECTOR CELL BONDING REAGENT Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1996-12-27 EP claimed
WO-1995024490-A1 CELL SURFACE PROTEIN AND EFFECTOR CELL BONDING REAGENT Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1995-09-14 WO claimed
EP-0367233-A2 Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1990-05-09 EP claimed
US-4874876-A ACYLATING THIOPHENE, REDUCING, HYDROLYZING OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-17 US claimed
JP-2196784-A None JP disclosed
JP-8067657-A None JP disclosed
EP-4585264-A2 HUMAN CGRP RECEPTOR BINDING PROTEINS AMGEN INC. (US) 2025-07-16 EP disclosed
CN-113908268-B Use of antibodies in the preparation of a medicament for the treatment or prevention of migraine 美国安进公司 2025-06-10 CN disclosed
US-20250163160-A1 Human Antigen Binding Proteins That Bind Beta-Klotho, FGF Receptors and Complexes Thereof AMGEN INC. 2025-05-22 US disclosed
US-12297260-B2 DKK1 antibodies and methods of use AMGEN INC. (US) 2025-05-13 US disclosed
US-4874876-A ACYLATING THIOPHENE, REDUCING, HYDROLYZING OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-17 US disclosed
US-4469768-A Electrophotographic light-sensitive material comprising a charge-generating material and a charge-transporting material FUJI PHOTO FILM CO., LTD. (JP) 1984-09-04 US disclosed
US-4443461-A N-[2-[[1-[1H-Indolylalkyl- or oxoalkyl]-4-piperidinyl]-amino]-2-oxoethyl]-arylcarboxamide derivatives JOHN WYETH & BROTHER LIMITED (GB) 1984-04-17 US disclosed
US-4373100-A ANIMAL FEEDS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1983-02-08 US disclosed
US-3987185-A INGIBITS ANTIGEN-ANTIBODY REACTIONS IN ANIMALS RICHARDSON-MERRELL INC. (US) 1976-10-19 US disclosed
JP-H00867657-A 0001-01-01 JP disclosed