Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 9/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169810 | 0.84 | MMP1 (0.53) | GNPATMMP2MMP8MMP9MMP3 | |
| SCHEMBL8169814 | 0.84 | MMP1 (0.53) | GNPATMMP2MMP8MMP9MMP3 | |
| SCHEMBL18237102 | 0.83 | CTSL (0.56) | GNPATKISS1RCTSL | |
| SCHEMBL14531809 | 0.81 | KISS1R (0.49) | GNPATMMP8KISS1RCTSLMMP1 | |
| SCHEMBL14598309 | 0.81 | NPY4R (0.52) | GNPATKISS1RCTSL | |
| SCHEMBL14509086 | 0.81 | GNPAT (0.48) | GNPATMMP8KISS1RCTSSCTSK | |
| SCHEMBL14598310 | 0.81 | NPY4R (0.52) | GNPATKISS1RCTSL | |
| SCHEMBL14509071 | 0.79 | KISS1R (0.51) | GNPATKISS1RCTSL | |
| SCHEMBL14509120 | 0.79 | NPY4R (0.55) | GNPATKISS1R | |
| SCHEMBL23376600 | 0.79 | CTSS (0.68) | GNPATMMP2MMP8MMP9CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |