SCHEMBL13596348

SCHEMBL13596348

O=CCCN(C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13596344 0.83 HIF1A (0.45) HIF1A
SCHEMBL7671376 0.74 ALDH1A1 (0.36) HIF1AALDH1A1
SCHEMBL13303092 0.69
SCHEMBL13181441 0.67 HIF1A (0.44) HIF1AALDH1A1
SCHEMBL2557742 0.67 ALDH1A1 (0.31) ALDH1A1
SCHEMBL196330 0.63
SCHEMBL285606 0.63
SCHEMBL13303094 0.63
SCHEMBL11001024 0.63 HIF1A (0.39) HIF1AALDH1A1
SCHEMBL9043970 0.63 CA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090320718-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090320718-A1 FLUOROSURFACTANTS FPR3, Q6ZSR9, SGMS2 HIF1A 4723/4885ALDH1A1 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.