Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13600969 | 1.00 | MEN1 (0.46) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL13600982 | 0.93 | MAPT (0.46) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4491609 | 0.92 | MMP1 (0.44) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4491610 | 0.92 | MMP1 (0.44) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4491605 | 0.92 | MMP1 (0.44) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4512228 | 0.85 | MAPT (0.46) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4512225 | 0.85 | MAPT (0.46) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4512222 | 0.85 | MAPT (0.46) | MEN1KMT2AMAPTTSHRMMP1 | |
| SCHEMBL4504773 | 0.83 | RXRA (0.52) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4504776 | 0.83 | RXRA (0.52) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |