Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13600970 | 0.93 | MEN1 (0.46) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL13600969 | 0.93 | MEN1 (0.46) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4512222 | 0.92 | MAPT (0.46) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4512225 | 0.92 | MAPT (0.46) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4512228 | 0.92 | MAPT (0.46) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4491605 | 0.85 | MMP1 (0.44) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4491609 | 0.85 | MMP1 (0.44) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4491610 | 0.85 | MMP1 (0.44) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4504773 | 0.83 | RXRA (0.52) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL4504776 | 0.83 | RXRA (0.52) | MAPTKMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |