Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495083 | 0.86 | MMP1 (0.56) | MAOALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL4495075 | 0.86 | MMP1 (0.56) | MAOALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL13600996 | 0.84 | SMN1; SMN2 (0.42) | MAOAMTNR1AMTNR1BLMNAALDH1A1 | |
| SCHEMBL4503457 | 0.71 | MMP1 (0.55) | MAOALMNANPC1RAB9AMMP1 | |
| SCHEMBL4503448 | 0.71 | MMP1 (0.55) | MAOALMNANPC1RAB9AMMP1 | |
| SCHEMBL4502463 | 0.70 | TSHR (0.48) | MAOALMNAALDH1A1NPC1KDM4E | |
| SCHEMBL4493327 | 0.70 | ALDH1A1 (0.50) | MAOALMNAALDH1A1NPC1KDM4E | |
| SCHEMBL4493330 | 0.67 | MAOA (0.47) | MAOALMNAALDH1A1NPC1KDM4E | |
| SCHEMBL4507435 | 0.66 | NPSR1 (0.47) | MAOALMNAALDH1A1NPC1KDM4E | |
| SCHEMBL20514054 | 0.66 | SMN1; SMN2 (0.69) | LMNAALDH1A1KDM4EMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |