Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MYB | P10242 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426684 | 0.81 | MAPK1 (0.61) | MAPK1HSD17B10L3MBTL1MYBALDH1A1 | |
| SCHEMBL4426708 | 0.78 | ALDH1A1 (0.57) | MAPK1HSD17B10L3MBTL1MYBALDH1A1 | |
| SCHEMBL8538963 | 0.78 | MYB (0.80) | L3MBTL1MYBKDM4EMAPTRAB9A | |
| SCHEMBL31237961 | 0.78 | MYB (0.80) | L3MBTL1MYBKDM4EMAPTRAB9A | |
| SCHEMBL4333621 | 0.78 | TUBB4A (0.64) | MYBSMN1; SMN2RAB9A | |
| SCHEMBL4425533 | 0.77 | MAPK1 (0.57) | MAPK1HSD17B10L3MBTL1MYBALDH1A1 | |
| SCHEMBL4320562 | 0.77 | MAPK1 (0.65) | MAPK1HSD17B10L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL31237204 | 0.77 | MAPK1 (0.65) | MAPK1HSD17B10L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4426920 | 0.76 | TUBB4A (0.66) | MAPK1HSD17B10L3MBTL1MYBALDH1A1 | |
| SCHEMBL4426296 | 0.76 | TUBB4A (0.66) | MAPK1HSD17B10L3MBTL1MYBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392683-B1 | SUBSTITUTED 4H-CHROMENES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THEIR USE AS ANTICANCER AGENTS | CYTOVIA INC (US) | 2009-12-02 | — | — | EP | disclosed |