Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601612 | 0.90 | ALDH1A1 (0.40) | DNM1ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL12773961 | 0.86 | ALDH1A1 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL9243638 | 0.86 | ALDH1A1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL12881668 | 0.86 | SMN1; SMN2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL12774034 | 0.86 | L3MBTL3 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL12774078 | 0.86 | BDKRB1 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL12881651 | 0.86 | SMN1; SMN2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL13601498 | 0.85 | DNM1 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL12881698 | 0.84 | ALDH1A1 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL26293215 | 0.83 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TSHRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137227-A1 | MULTI-VESICULAR LIPID NANOPARTICLE TOLEROGENIC VACCINES FOR INDUCTION OF SYSTEMIC IMMUNE TOLERANCE IN VIVO | KARMA BIOTECHNOLOGIES (US) | 2023-07-20 | — | — | WO | disclosed |
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |