Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601647 | 0.78 | ACMSD (0.50) | DHODHKDM4EALDH1A1LDHA | |
| SCHEMBL23365598 | 0.76 | AKR1C3 (0.47) | DHODHSLC22A12CYP46A1ALDH1A1LDHA | |
| SCHEMBL23365596 | 0.75 | KDM4E (0.52) | DHODHKDM4ELDHA | |
| SCHEMBL13601631 | 0.73 | LDHA (0.49) | DHODHMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL13601650 | 0.73 | DHODH (0.47) | DHODHKDM4EALDH1A1 | |
| SCHEMBL82604 | 0.71 | KDM4C (0.59) | TDP1SLC22A12KDM4CKDM4EKDM6B | |
| SCHEMBL29578794 | 0.71 | KDM4C (0.59) | TDP1SLC22A12KDM4CKDM4EKDM6B | |
| SCHEMBL258230 | 0.71 | TDP1 (0.68) | DHODHTDP1SIRT3KDM4CKDM4E | |
| SCHEMBL29571308 | 0.71 | TDP1 (0.68) | DHODHTDP1SIRT3KDM4CKDM4E | |
| SCHEMBL16345539 | 0.71 | CYP3A4 (0.43) | DHODHSLC22A12GPBAR1KDM4CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | DHODH 2603/4885TDP1 1668/4885SIRT3 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.