SCHEMBL82604

SCHEMBL82604

O=C(O)c1ccncc1F

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 16/20 0.59
KDM6B O15054 9/20 0.59
KDM4D Q6B0I6 5/20 0.59
KDM4E B2RXH2 4/20 0.59
KDM4A O75164 2/20 0.59
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 1/20 0.59
MAPT P10636 1/20 0.59
THRB P10828 1/20 0.59
KMT2A Q03164 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
ASPH Q12797 2/20 0.47
KDM8 Q8N371 2/20 0.47
EGLN3 Q9H6Z9 1/20 0.44
KDM5B Q9UGL1 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
SLC22A12 Q96S37 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29578794 1.00 KDM4C (0.59) KDM4CKDM6BKDM4DKDM4EKDM4A
Hydrochloric Acid SCHEMBL1027857 0.98 KDM4C (0.57) KDM4CKDM6BKDM4DKDM4EKDM4A
Nitrous Acid SCHEMBL28904582 0.92 KDM4C (0.52) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL8686759 0.88 ROCK2 (0.47) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL229353 0.83 KDM4C (0.53) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL30316868 0.83 KDM4C (0.53) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL25201864 0.81 KDM4C (0.42) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL459712 0.81 LOXL2 (0.44) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL724581 0.81 ALDH1A1 (0.52) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL2618803 0.81 TDP1 (0.55) KDM4CKDM6BKDM4DKDM4EKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 702 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037226-A Bimetallic-organic framework material for trapping trifluoromethane, preparation method thereof and adsorbent based on bimetallic-organic framework material 西安交通大学 2026-05-15 CN claimed
CN-118420919-A Metal organic framework material with trivalent boron blocked Lewis acid-base pair with fixed structures at two ends, preparation method and application thereof 武汉大学 2024-08-02 CN claimed
CN-118007162-A Preparation method of carbon dioxide electro-reduction catalyst 中汽研汽车检验中心(天津)有限公司 2024-05-10 CN claimed
CN-116936810-B Positive pole piece of sodium ion battery and sodium ion battery 天鹏锂能技术(淮安)有限公司 2023-12-12 CN claimed
CN-116936810-A Positive pole piece of sodium ion battery and sodium ion battery 天鹏锂能技术(淮安)有限公司 2023-10-24 CN claimed
CN-116574270-A Cobalt-based metal organic framework material and preparation method and application thereof 吉林大学 2023-08-11 CN claimed
CN-111072987-B Two fluorinated metal organic framework materials, preparation and low-carbon hydrocarbon separation application thereof 北京工业大学 2022-02-15 CN claimed
CN-111072987-A Two fluorinated metal organic framework materials, preparation and low-carbon hydrocarbon separation application thereof 北京工业大学 2020-04-28 CN claimed
CN-110818629-A Method for synthesizing fluoroisonicotinic acid derivative 杭州勇诚睿生物科技有限公司 2020-02-21 CN claimed
US-20150005320-A9 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES SYNTA PHARMACEUTICALS CORP. (US) 2015-01-01 US claimed
EP-1651232-A4 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES SYNTA PHARMACEUTICALS CORP (US) 2007-06-06 EP claimed
EP-1653968-A4 METHOD FOR MODULATING CALCIUM ION-RELEASE-ACTIVATED CALCIUM ION CHANNELS SYNTA PHARMACEUTICALS CORP (US) 2006-09-06 EP claimed
CN-1826121-A Method for regulating and controlling calcium ion release to activate calcium ion channel SYNTA PHARMACEUTICALS CORP (US) 2006-08-30 CN claimed
CN-1826120-A Compounds for inflammation and immune-related uses SYNTA PHARMACEUTICALS CORP (US) 2006-08-30 CN claimed
EP-1653968-A2 METHOD FOR MODULATING CALCIUM ION-RELEASE-ACTIVATED CALCIUM ION CHANNELS Synta Pharmaceuticals Corporation (US) 2006-05-10 EP claimed
EP-1651232-A2 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES Synta Pharmaceuticals Corporation (US) 2006-05-03 EP claimed
US-20050148633-A1 Calcium channel blockers and releasing ions for prodrugs SYNTA PHARMACEUTICALS CORP. 2005-07-07 US claimed
US-20050107436-A1 phenyl and pyridyl derivatives such as 3-Fluoro-N-(2'-trifluoromethyl-biphenyl-4-yl)-isonicotinamide, used as immunosuppressants for the treatmet or prevent inflammatory and immune disorders SYNTA PHARMACEUTICALS CORP. 2005-05-19 US claimed
WO-2005009954-A2 METHOD FOR MODULATING CALCIUM ION-RELEASE-ACTIVATED CALCIUM ION CHANNELS SYNTA PHARMACEUTICALS, CORP. (US) 2005-02-03 WO claimed
WO-2005009539-A2 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES SYNTA PHARMACEUTICALS, CORP. (US) 2005-02-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148633-A1 Calcium channel blockers and releasing ions for prodrugs ORAI1, CACNA1C, CACNA1F KDM4C 1567/4885KDM6B 1768/4885KDM4D 2708/4885
US-20150005320-A9 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES CXCR2, CXCL8, CCR9 KDM4C 3557/4885KDM6B 2111/4885KDM4D 3444/4885
US-20050107436-A1 phenyl and pyridyl derivatives such as 3-Fluoro-N-(2'-trifluoromethyl-biphenyl-4-yl)-isonicotinamide, used as immunosuppressants for the treatmet or prevent inflammatory and immune disorders TPMT, PTPN3, FKBP3 KDM4C 1774/4885KDM6B 1012/4885KDM4D 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.