Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997973 | 0.87 | HRH3 (0.47) | OPRM1OPRD1OPRK1HRH3JAK2 | |
| SCHEMBL12653312 | 0.80 | OPRM1 (0.46) | OPRM1OPRD1OPRK1HRH3HRH1 | |
| SCHEMBL21541214 | 0.79 | ACACB (0.42) | — | |
| SCHEMBL24023602 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL778932 | 0.77 | NPC1 (0.49) | OPRM1OPRD1HRH3HRH1 | |
| SCHEMBL13604922 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL12808386 | 0.76 | MEN1 (0.53) | HRH3 | |
| SCHEMBL13913007 | 0.76 | ACACB (0.44) | HRH3 | |
| SCHEMBL328389 | 0.74 | HRH3 (0.46) | HRH3HRH1 | |
| SCHEMBL14380137 | 0.74 | ALDH1A1 (0.57) | OPRM1OPRD1OPRK1HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629341-B2 | e.g. N1-hydroxy-N2-[(4-phenoxyphenyl)sulfonyl]-D-argininamide; metallopeptidase inhibitor; antiinflammation, anticarcinogenic, antidiabetic agent; angiogenesis inhibitor; atherosclerosis, stroke, ulcer, infertility, scleroderma, endometriosis, mesothelioma | SYMPHONY EVOLUTION, INC. (US) | 2009-12-08 | — | — | US | disclosed |