Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511725 | 0.91 | HTR2C (0.38) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL4875106 | 0.83 | CSNK2B (0.32) | TP53LMNAMAPT | |
| SCHEMBL13606367 | 0.83 | GBA1 (0.40) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL4513969 | 0.83 | GBA1 (0.40) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL13606365 | 0.80 | GBA1 (0.40) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL4499877 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2ATP53KDM4EHSD17B10 | |
| SCHEMBL4511720 | 0.74 | HTR2C (0.39) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL13606366 | 0.74 | HTR2C (0.39) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL4874084 | 0.73 | GBA1 (0.39) | GBA1MEN1KMT2ATP53KDM4E | |
| SCHEMBL4493601 | 0.73 | TP53 (0.39) | MEN1KMT2ATP53KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | GBA1 2709/4885MEN1 2381/4885KMT2A 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.