Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512702 | 0.92 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL4507101 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3713237 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL4494543 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3706568 | 0.75 | AKT1 (0.50) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL4509127 | 0.73 | TP53 (0.43) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL13232454 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL4502203 | 0.73 | TP53 (0.44) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3716845 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3536164 | 0.71 | DPP4 (0.43) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |