Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360586 | 0.81 | MAPT (0.33) | OGG1POLBTDP1MAPTKMT2A | |
| SCHEMBL1701448 | 0.80 | POLB (0.54) | POLBMAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9780822 | 0.80 | TDP1 (0.55) | OGG1TDP1TSHRHTR2AHTR2C | |
| SCHEMBL1360515 | 0.80 | TDP1 (0.55) | OGG1TDP1TSHRHTR2AHTR2C | |
| SCHEMBL1359803 | 0.76 | SMN1; SMN2 (0.39) | POLBCYP2D6TSHRHTR2AMAPT | |
| SCHEMBL10359367 | 0.74 | TSHR (0.38) | OGG1POLBCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL12363682 | 0.73 | TSHR (0.42) | CYP2D6SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL10875396 | 0.72 | GAA (0.50) | POLBTDP1TSHRKMT2ACYP1A2 | |
| SCHEMBL14121949 | 0.71 | TDP1 (0.53) | OGG1TDP1TSHRHTR2AHTR2C | |
| SCHEMBL11070481 | 0.70 | GABRA1 (0.38) | OGG1POLBTSHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067592-B2 | N-alkyny-2-(substituted aryloxy) alkylthioamine derivatives as fungicides | SYNGENTA LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| EP-1638928-B1 | N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | SYNGENTA LTD (GB) | 2010-09-29 | — | — | EP | disclosed |
| US-20070042996-A1 | N-alkynyl-2-(substituted aryloxy) alkylthioamine derivatives as fungicides | SYNGENTA LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
| EP-1638928-A1 | N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | Syngenta Limited (GB) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108663-A1 | N-ALKYNYL-2- (SUBSTITUTED ARYLOXY) ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042996-A1 | N-alkynyl-2-(substituted aryloxy) alkylthioamine derivatives as fungicides | NAT1, AKR7A2, KCNA2 | OGG1 2839/4885POLB 4255/4885CYP2D6 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.