SCHEMBL11070481

SCHEMBL11070481

CC(O)Oc1cc(Cl)cc(OC(C)O)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
OGG1 O15527 1/20 0.36
RHEB Q15382 1/20 0.34
MAPT P10636 1/20 0.32
HTR2A P28223 2/20 0.32
DRD2 P14416 1/20 0.32
HTR7 P34969 1/20 0.32
HTR6 P50406 1/20 0.32
TSHR P16473 2/20 0.32
POLB P06746 1/20 0.32
FFAR4 Q5NUL3 3/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10359367 0.95 TSHR (0.38) GABRA1GABRB1OGG1RHEBMAPT
SCHEMBL15321754 0.87 ALDH1A1 (0.35) KMT2A
SCHEMBL11682199 0.81 ALDH1A3 (0.38) OGG1MAPTFFAR4KMT2A
SCHEMBL10359303 0.79 HPGD (0.39) TSHR
SCHEMBL10359842 0.79 OGG1 (0.58) OGG1MAPTKMT2AL3MBTL1
SCHEMBL1885211 0.77 L3MBTL1 (0.45) OGG1MAPTTSHRPOLBL3MBTL1
SCHEMBL8333706 0.76 POLB (0.52) POLBL3MBTL1SIGMAR1
SCHEMBL12363682 0.75 TSHR (0.42) GABRA1GABRB1MAPTHTR2ADRD2
SCHEMBL10358719 0.74 CYP1A2 (0.41) GABRA1GABRB1MAPTTSHRPOLB
SCHEMBL10359826 0.73 ALDH1A1 (0.39) MAPTTSHRPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4468510-A FILMS, FIBERS, MOLDING PLASTICS, LOW GAS PERMEABILITY EASTMAN KODAK COMPANY (US) 1984-08-28 US disclosed