SCHEMBL13607353

CC(C)(C)[Si](OC[C@]12CC3(OCc4ccccc4)OCO[C@@H](C31)[C@H](n1ccc(NC(=O)c3ccccc3)nc1=O)O2)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ABL1	P00519	1/20	0.38

▸	RIN1	Q13671	1/20	0.38

▸	P2RY6	Q15077	9/20	0.38

▸	P2RY14	Q15391	2/20	0.38

▸	NT5E	P21589	1/20	0.38

▸	POLB	P06746	1/20	0.37

▸	P2RY2	P41231	4/20	0.33

▸	P2RY4	P51582	4/20	0.33

▸	USP30	Q70CQ3	1/20	0.32

▸	P2RY12	Q9H244	1/20	0.31

▸	CYP3A4	P08684	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13607349	0.87	ABL1 (0.46)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL13607352	0.75	P2RY6 (0.44)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL13607348	0.73	P2RY6 (0.38)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL13607347	0.72	ABL1 (0.50)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL1096917	0.71	ABL1 (0.47)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL13615887	0.71	P2RY6 (0.43)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL4778644	0.70	ABL1 (0.45)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL16639166	0.69	ABL1 (0.46)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL13881302	0.69	ABL1 (0.46)	ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL26122578	0.68	ABL1 (0.43)	ABL1RIN1P2RY6P2RY14NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7615619-B2	Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof	TAKESHI IMANISHI (JP)	2009-11-10	—	—	US	disclosed