Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 7/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096958 | 0.89 | P2RY6 (0.42) | P2RY6P2RY14NT5EPOLBABL1 | |
| SCHEMBL13607352 | 0.84 | P2RY6 (0.44) | P2RY6P2RY14NT5EPOLBABL1 | |
| SCHEMBL26122705 | 0.82 | P2RY6 (0.42) | P2RY6P2RY14NT5EPOLBABL1 | |
| SCHEMBL26122701 | 0.82 | P2RY6 (0.42) | P2RY6P2RY14NT5EPOLBABL1 | |
| SCHEMBL26125331 | 0.81 | POLB (0.45) | P2RY6P2RY14NT5EPOLBABL1 | |
| SCHEMBL26125336 | 0.81 | POLB (0.45) | P2RY6P2RY14NT5EPOLBABL1 | |
| SCHEMBL13607350 | 0.78 | LMNA (0.36) | POLBGSTP1ABCB1 | |
| SCHEMBL20394004 | 0.78 | TDP1 (0.40) | P2RY6NT5EP2RY2P2RY4TDP1 | |
| SCHEMBL20394005 | 0.78 | TDP1 (0.40) | P2RY6NT5EP2RY2P2RY4TDP1 | |
| SCHEMBL4082341 | 0.77 | TDP1 (0.36) | NT5ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615619-B2 | Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof | TAKESHI IMANISHI (JP) | 2009-11-10 | — | — | US | disclosed |