SCHEMBL13609357

SCHEMBL13609357

CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@]1(C)CCC(=O)C[C@@]21C

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 15/20 0.51
▸ CNR1 P21554 13/20 0.51
▸ NR1I2 O75469 1/20 0.51
▸ ADORA3 P0DMS8 1/20 0.51
▸ SLC6A3 Q01959 1/20 0.51
▸ DRD3 P35462 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13609358 0.80 DRD3 (0.52) CNR2CNR1DRD3
SCHEMBL10367356 0.71 CNR2 (0.47) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL10365544 0.71 CNR1 (0.57) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31545670 0.71 CNR2 (0.53) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL11268356 0.70 CNR2 (0.87) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL19281379 0.70 CNR1 (0.56) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL17843951 0.69 CNR2 (0.52) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL7258490 0.68 CNR1 (0.62) CNR2CNR1
Nabilone SCHEMBL15520922 0.67 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
Nabilone SCHEMBL563809 0.67 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275649-A1 Compositions And Methods For Identifying Modulars Of TRPV2 QIN NING 2009-11-05 — — US disclosed
US-20090275649-A1 Compositions And Methods For Identifying Modulars Of TRPV2 QIN NING 2009-11-05 — — US disclosed
US-7575882-B2 Compositions and methods for identifying modulators of TRPV2 JANSSEN PHARMACEUTICA N. V. (BE) 2009-08-18 — — US disclosed
US-7575882-B2 Compositions and methods for identifying modulators of TRPV2 JANSSEN PHARMACEUTICA N. V. (BE) 2009-08-18 — — US disclosed
US-20070105086-A1 Compositions and methods for identifying modulators of TRPV2 JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-10 — — US disclosed
US-20070105086-A1 Compositions and methods for identifying modulators of TRPV2 JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275649-A1 Compositions And Methods For Identifying Modulars Of TRPV2 TRPV2, TRPV1, TRPV3 CNR2 8/4885CNR1 21/4885NR1I2 1772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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