SCHEMBL13610016

SCHEMBL13610016

COC(=O)CC(C)CCc1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HTT P42858 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HPGD P15428 1/20 0.45
DPP4 P27487 1/20 0.45
TSHR P16473 1/20 0.43
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13079708 0.86 OPRK1 (0.44) KMT2AMEN1HTTKDM4EMAPK1
SCHEMBL11576249 0.86 CYP4F2 (0.60) MAPTALDH1A1L3MBTL1TSHRCYP4F2
SCHEMBL4654958 0.84 MAPT (0.47) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL28200415 0.84 HTT (0.49) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL4206102 0.84 TSHR (0.53) KMT2AMEN1ALDH1A1HTTHPGD
SCHEMBL14338691 0.84 TSHR (0.53) KMT2AMEN1ALDH1A1HTTHPGD
SCHEMBL14593493 0.84 MEN1 (0.50) KMT2AMEN1KDM4EL3MBTL1
SCHEMBL11575570 0.83 MMP12 (0.50) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL13610028 0.82 TP53 (0.47) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL27575742 0.82 MMP12 (0.46) KDM4ECYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615233-B2 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KABUSHIKI KAISHA (JP) 2009-11-10 US disclosed
US-7527809-B2 Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed