Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118326 | 0.86 | MAPT (0.48) | NPC1RAB9AHTR7KMT2AMEN1 | |
| SCHEMBL5178522 | 0.85 | NPC1 (0.49) | NPC1RAB9AHTR7KMT2AMEN1 | |
| SCHEMBL13610020 | 0.85 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL640759 | 0.79 | LMNA (0.60) | NPC1RAB9AHTR7KMT2AMEN1 | |
| SCHEMBL24233758 | 0.79 | NPC1 (0.51) | NPC1RAB9AHTR7KMT2AMEN1 | |
| SCHEMBL13610016 | 0.79 | KMT2A (0.47) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL17032601 | 0.77 | NPC1 (0.62) | NPC1RAB9AHTR7KMT2AMEN1 | |
| SCHEMBL14593406 | 0.77 | EPHX2 (0.46) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL1533298 | 0.76 | NPC1 (0.72) | NPC1RAB9AHTR7KMT2AMEN1 | |
| SCHEMBL6814347 | 0.76 | NPC1 (0.67) | NPC1RAB9AHTR7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615233-B2 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | CANON KABUSHIKI KAISHA (JP) | 2009-11-10 | — | — | US | disclosed |
| US-7527809-B2 | Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof | CANON KABUSHIKI KAISHA (JP) | 2009-05-05 | — | — | US | disclosed |