SCHEMBL13610020

SCHEMBL13610020

COC(=O)CC(C)CCC(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.51
SIGMAR1 Q99720 1/20 0.46
KCNA5 P22460 1/20 0.45
L3MBTL1 Q9Y468 5/20 0.44
MAPT P10636 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
LMNA P02545 2/20 0.44
NR4A2 P43354 1/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 2/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
CES1 P23141 1/20 0.44
MAPK1 P28482 1/20 0.44
AKT1 P31749 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13610023 0.85 NPC1 (0.49) KMT2AL3MBTL1MAPTLMNAPOLB
SCHEMBL15661338 0.78 L3MBTL1 (0.52) KMT2ASIGMAR1L3MBTL1MAPTTDP1
SCHEMBL10345707 0.78 L3MBTL1 (0.52) KMT2ASIGMAR1L3MBTL1MAPTTDP1
SCHEMBL135356 0.78 NR4A2 (0.61) KMT2AL3MBTL1MAPTTDP1LMNA
SCHEMBL4206102 0.78 TSHR (0.53) KMT2AHTTMEN1HPGDSMN1; SMN2
SCHEMBL14338691 0.78 TSHR (0.53) KMT2AHTTMEN1HPGDSMN1; SMN2
SCHEMBL27667390 0.77 L3MBTL1 (0.51) KMT2ASIGMAR1L3MBTL1MAPTTDP1
SCHEMBL13610025 0.77 ALDH1A1 (0.59) KMT2AL3MBTL1MAPTLMNAPOLB
SCHEMBL8326296 0.76 TSHR (0.48) MAPTTSHR
SCHEMBL725762 0.76 TRPA1 (0.58) KMT2ASIGMAR1L3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615233-B2 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KABUSHIKI KAISHA (JP) 2009-11-10 US disclosed
US-7527809-B2 Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed