Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610193 | 0.88 | ALDH1A1 (0.40) | MTNR1AALDH1A1TDP1NOS1HTR1A | |
| SCHEMBL22977707 | 0.83 | MTNR1A (0.52) | MTNR1AALDH1A1BRD4CREBBPCYP1A2 | |
| SCHEMBL8553887 | 0.83 | MTNR1A (0.52) | MTNR1AALDH1A1BRD4CREBBPCYP1A2 | |
| SCHEMBL29593079 | 0.83 | MTNR1A (0.52) | MTNR1AALDH1A1BRD4CREBBPCYP1A2 | |
| SCHEMBL4128722 | 0.81 | MTNR1A (0.53) | MTNR1AALDH1A1HTR1ABRD4CREBBP | |
| SCHEMBL4045997 | 0.80 | MTNR1A (0.55) | MTNR1AALDH1A1HTR1ABRD4CREBBP | |
| SCHEMBL13384188 | 0.78 | MTNR1A (0.52) | MTNR1ABRD4CREBBP | |
| SCHEMBL4138599 | 0.76 | MTNR1A (0.57) | MTNR1AHTR1ABRD4CREBBP | |
| SCHEMBL4139663 | 0.76 | MTNR1A (0.60) | MTNR1AHTR1ABRD4CREBBP | |
| SCHEMBL22262591 | 0.76 | MTNR1A (0.60) | MTNR1AHTR1ABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |