Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568800 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2 | |
| SCHEMBL8562575 | 0.80 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1EPHX2CYP1A2 | |
| SCHEMBL8562571 | 0.80 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1EPHX2CYP1A2 | |
| SCHEMBL8562578 | 0.80 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1EPHX2CYP1A2 | |
| SCHEMBL13610193 | 0.78 | ALDH1A1 (0.40) | MTNR1AALDH1A1TDP1NOS1CYP1A2 | |
| SCHEMBL8562991 | 0.78 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2 | |
| SCHEMBL8562997 | 0.78 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2 | |
| SCHEMBL8561678 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2 | |
| SCHEMBL7418105 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2 | |
| SCHEMBL18406697 | 0.77 | POLB (0.37) | MTNR1AMTNR1BALDH1A1CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |