Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562578 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2AIDH1 | |
| SCHEMBL8562571 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2AIDH1 | |
| SCHEMBL8568454 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL7422364 | 0.82 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL7422361 | 0.82 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL13610207 | 0.80 | MTNR1A (0.46) | MTNR1AMTNR1BEPHX2ALDH1A1CYP1A2 | |
| SCHEMBL7263051 | 0.79 | IDO1 (0.48) | DRD3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13305786 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL5539883 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL8569794 | 0.78 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |