Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL29206935 | 0.98 | LMNA (0.43) | CYP3A4CYP2D6LMNANPC1SMN1; SMN2 | |
| Butane SCHEMBL29206957 | 0.96 | LMNA (0.42) | CYP3A4CYP2D6LMNANPC1SMN1; SMN2 | |
| 1-Bromobutane SCHEMBL29206954 | 0.92 | LMNA (0.40) | CYP3A4CYP2D6LMNANPC1SMN1; SMN2 | |
| SCHEMBL10264180 | 0.84 | CYP3A4 (0.41) | CYP3A4CYP2D6LMNANPC1SMN1; SMN2 | |
| SCHEMBL14101264 | 0.84 | LOXL2 (0.42) | CYP3A4CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12743775 | 0.81 | HRH1 (0.52) | CYP3A4CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6685708 | 0.81 | L3MBTL1 (0.58) | CYP3A4SMN1; SMN2L3MBTL1TDP1MEN1 | |
| SCHEMBL19827229 | 0.81 | TDP1 (0.46) | CYP3A4LMNANR5A1L3MBTL1TDP1 | |
| SCHEMBL7120703 | 0.81 | L3MBTL1 (0.58) | CYP3A4SMN1; SMN2L3MBTL1TDP1MEN1 | |
| SCHEMBL21081916 | 0.81 | L3MBTL1 (0.58) | CYP3A4SMN1; SMN2L3MBTL1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |