Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20861827 | 0.83 | MYC (0.50) | HSP90AB1HTR7ALDH1A1GAAGFER | |
| SCHEMBL13611183 | 0.82 | GAA (0.44) | HSP90AB1HTR7ALDH1A1GAAGFER | |
| SCHEMBL4387429 | 0.78 | ALDH1A1 (0.47) | HTR7ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL4374369 | 0.73 | NPSR1 (0.42) | HTR7ALDH1A1GAAMAPTTSHR | |
| SCHEMBL30096935 | 0.72 | GAA (0.68) | HSP90AB1ALDH1A1GAAGFERMAPT | |
| SCHEMBL2127019 | 0.72 | GAA (0.68) | HSP90AB1ALDH1A1GAAGFERMAPT | |
| SCHEMBL1786183 | 0.71 | NPC1 (0.63) | HSP90AB1HTR7ALDH1A1GAAGFER | |
| SCHEMBL4467294 | 0.70 | POLB (0.41) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2706645 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MAPTTSHRHPGDSMN1; SMN2 | |
| SCHEMBL12062913 | 0.69 | ALDH1A1 (0.54) | HSP90AB1HTR7ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |