SCHEMBL13610604

SCHEMBL13610604

O=C(CS)OCC(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.50
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
FABP7 O15540 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13610599 0.81 HTT (0.46) HTTTSHRHSD17B10FABP7MEN1
SCHEMBL7510764 0.79 HTT (0.54) HTTTSHRHSD17B10FABP7CA1
SCHEMBL60561 0.79 TSHR (0.43) TSHRHSD17B10ALDH1A1
SCHEMBL4951808 0.79 HTT (0.54) HTTTSHRHSD17B10FABP7CA1
SCHEMBL13610606 0.78 TSHR (0.34) HTTTSHRHSD17B10
SCHEMBL13610602 0.78 TSHR (0.44) HTTTSHRHSD17B10MEN1ALDH1A1
SCHEMBL14244347 0.77 HTT (0.52) HTTTSHRHSD17B10FABP7CA1
SCHEMBL28595777 0.77 HTT (0.52) HTTTSHRHSD17B10FABP7CA1
SCHEMBL974754 0.77 HTT (0.52) HTTTSHRHSD17B10FABP7CA1
SCHEMBL13610616 0.76 HTT (0.42) HTTTSHRHSD17B10MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7623751-B2 Compound, polymerizable composition, optical device, and method for producing refractive index profile optical device FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-7623751-B2 Compound, polymerizable composition, optical device, and method for producing refractive index profile optical device FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-20080226244-A1 Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080226244-A1 Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080226244-A1 Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device PIEZO1, PFN1, INF2 HTT 4033/4885TSHR 2398/4885HSD17B10 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.