SCHEMBL13610606

SCHEMBL13610606

O=C(CS)OCC(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13610601 0.84
SCHEMBL13610611 0.81 TSHR (0.38) TSHRHSD17B10HTT
SCHEMBL20130423 0.79 NAAA (0.36) HTT
SCHEMBL8578385 0.79 HTT (0.30) HTT
SCHEMBL13610604 0.78 HTT (0.50) TSHRHSD17B10HTT
SCHEMBL2297439 0.78 HTT (0.34) HTT
SCHEMBL1435255 0.76 THRB (0.36) HTT
SCHEMBL27220795 0.76 HTT (0.33) HTT
SCHEMBL11649749 0.75 THRB (0.37) HTT
SCHEMBL5704616 0.74 ALDH1A1 (0.39) TSHRHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7623751-B2 Compound, polymerizable composition, optical device, and method for producing refractive index profile optical device FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-20080226244-A1 Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080226244-A1 Compound, Polymerizable Composition, Optical Device, and Method for Producing Refractive Index Profile Optical Device PIEZO1, PFN1, INF2 TSHR 2398/4885HSD17B10 3682/4885HTT 4033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.