Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296199 | 0.87 | L3MBTL1 (0.91) | ALDH1A1L3MBTL1SMN1; SMN2PTGDR2NPSR1 | |
| SCHEMBL13623674 | 0.86 | ALDH1A1 (0.80) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4295684 | 0.84 | L3MBTL1 (0.69) | ALDH1A1L3MBTL1SMN1; SMN2PTGDR2NPSR1 | |
| SCHEMBL13610834 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1SMN1; SMN2PTGDR2NPSR1 | |
| SCHEMBL5115401 | 0.73 | PTGDR2 (1.00) | L3MBTL1PTGDR2POLB | |
| SCHEMBL5120272 | 0.73 | PTGDR2 (1.00) | L3MBTL1PTGDR2POLB | |
| SCHEMBL10834022 | 0.72 | TLR8 (0.68) | ALDH1A1SMN1; SMN2NPSR1SAE1UBA2 | |
| SCHEMBL226014 | 0.72 | TLR8 (0.66) | ALDH1A1SMN1; SMN2NPSR1SAE1UBA2 | |
| SCHEMBL28372897 | 0.72 | TLR8 (0.64) | ALDH1A1SMN1; SMN2NPSR1SAE1UBA2 | |
| SCHEMBL28378368 | 0.72 | TLR8 (0.64) | ALDH1A1SMN1; SMN2NPSR1SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | ALDH1A1 2368/4885L3MBTL1 4358/4885SMN1; SMN2 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.