Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285315 | 0.89 | NR3C1 (0.55) | NR3C1CYP11B1CYP11B2SMO | |
| SCHEMBL4275048 | 0.81 | NR3C1 (0.61) | NR3C1SMO | |
| SCHEMBL13611160 | 0.81 | NR3C1 (0.42) | NR3C1SMO | |
| SCHEMBL27724526 | 0.80 | NR3C1 (0.47) | NR3C1CYP11B1CYP11B2SMO | |
| SCHEMBL13611162 | 0.80 | POLB (0.43) | NR3C1SMO | |
| SCHEMBL13611161 | 0.79 | NR3C1 (0.41) | NR3C1CYP11B1CYP11B2SMO | |
| SCHEMBL4764413 | 0.77 | NR3C1 (0.50) | NR3C1CYP11B1CYP11B2SMO | |
| SCHEMBL4281429 | 0.77 | NR3C1 (0.59) | NR3C1CYP11B1CYP11B2SMO | |
| SCHEMBL4279204 | 0.74 | NR3C1 (0.58) | NR3C1CYP11B1CYP11B2SMO | |
| SCHEMBL3003795 | 0.74 | NR3C1 (0.63) | NR3C1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622594-B2 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |