Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802576 | 0.89 | MAPK1 (0.37) | MAPK1HIF1ATSHRCYP3A4PRSS1 | |
| SCHEMBL12152613 | 0.88 | MAPK1 (0.40) | MAPK1HIF1ATSHRCYP3A4CYP1A2 | |
| SCHEMBL13611320 | 0.87 | TSHR (0.41) | MAPK1TSHRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL13611326 | 0.84 | PRSS1 (0.45) | MAPK1TSHRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL13611354 | 0.84 | PRSS1 (0.47) | MAPK1TSHRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL13611328 | 0.83 | SERPINE1 (0.40) | MAPK1TSHRCYP3A4PRSS1PRSS2 | |
| SCHEMBL13611329 | 0.83 | PRSS1 (0.44) | MAPK1TSHRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL2350932 | 0.82 | ALDH1A1 (0.44) | MAPK1TSHRCYP3A4NPC1RAB9A | |
| SCHEMBL12152615 | 0.81 | MAPK1 (0.37) | MAPK1HIF1ATSHRCYP3A4CYP1A2 | |
| SCHEMBL16270514 | 0.81 | PRSS1 (0.43) | HIF1ATSHRCYP3A4CYP1A2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367747-B2 | Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367747-B2 | Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, L.L.C (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, L.L.C (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | PUF60, PFAS, UROD | MAPK1 4264/4885HIF1A 1801/4885TSHR 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.