Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611409 | 0.91 | PDK2 (0.38) | KMT2AFABP5NR1H3MAOBALDH1A1 | |
| SCHEMBL15417653 | 0.88 | MEN1 (0.44) | KMT2AALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL13625096 | 0.82 | MAOB (0.38) | MAOB | |
| SCHEMBL28901513 | 0.80 | ALDH1A1 (0.46) | KMT2AFABP5ALDH1A1LMNAHTT | |
| SCHEMBL29363915 | 0.80 | ALDH1A1 (0.46) | KMT2AFABP5ALDH1A1LMNAHTT | |
| SCHEMBL30883356 | 0.78 | PTPN1 (0.38) | KMT2AFABP5FFAR4PTPN1ALDH1A1 | |
| SCHEMBL28691528 | 0.77 | PTPN1 (0.37) | KMT2AFABP5FFAR4NR1H3PTPN1 | |
| SCHEMBL13010922 | 0.77 | CNR1 (0.41) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7169749 | 0.77 | KMT2A (0.44) | KMT2AFABP5FFAR4LMNAS1PR1 | |
| SCHEMBL17244742 | 0.76 | CNR1 (0.43) | NR1H3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623606-B2 | Screening method for GPCR ligands | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-01-07 | — | — | US | disclosed |
| US-8623606-B2 | Screening method for GPCR ligands | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-01-07 | — | — | US | disclosed |
| US-20090286259-A1 | SCREENING METHOD FOR GPCR LIGANDS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2009-11-19 | — | — | US | disclosed |
| US-20090286259-A1 | SCREENING METHOD FOR GPCR LIGANDS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2009-11-19 | — | — | US | disclosed |
| WO-2008022716-A2 | SCREENING METHOD FOR GPCR LIGANDS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286259-A1 | SCREENING METHOD FOR GPCR LIGANDS | GPR139, GRK2, GPR27 | KMT2A 3694/4885FABP5 332/4885FFAR4 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.