SCHEMBL13612619

SCHEMBL13612619

CCN(CC)c1ccc(N=Nc2ccc(N=Nc3nc4ccc(C)cc4s3)c(C)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.48
INSR P06213 4/20 0.48
RAB9A P51151 7/20 0.47
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
NPC1 O15118 5/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
APP P05067 2/20 0.47
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
MAPK1 P28482 2/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
PSMD14 O00487 1/20 0.33
MITF O75030 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17131760 0.91 MAPT (0.56) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL19760855 0.89 INSR (0.48) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL3437405 0.88 INSR (0.59) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL16252392 0.85 MAPT (0.61) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL14198812 0.82 MAPT (0.43) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL25486495 0.81 MAPT (0.51) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL24046596 0.79 INSR (0.76) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL10904886 0.79 MAPT (0.55) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL19935504 0.78 MAPT (0.52) MAPTINSRRAB9AKMT2AMEN1
SCHEMBL19736224 0.78 MAPT (0.74) MAPTINSRRAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274853-A1 DICHROIC DYE COMPOSITION C1S, CDY1; CDY1B, CRY1 MAPT 2754/4885INSR 1209/4885RAB9A 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.